Jatun Mayu (Quechua hatun, jatun big, great, mayu river,[1] "great river") is a Bolivian river in the Cochabamba Department, Tiraque Province, Tiraque Municipality[2] and south of it in the Arani Province, Vacas Municipality. It is one of the most important tributaries of Parqu Qucha, a lake north west of Vacas.[3] It originates north east of Punata.[4] It changes its directions from north west to north, then near Palca it abruptly turns to the south east.

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